The in-silico feasibility of dose escalated, hypofractionated radiotherapy for rectal cancer

The in-silico feasibility of dose escalated, hypofractionated radiotherapy for rectal cancer

Background and purpose: Short course radiotherapy (SCRT) has a low biological prescription dose. Rectal cancer has a dose response relationship and moderate α/β ratio (∼5). We hypothesise hypofractionated dose escalation has radiobiological advantages. We assessed in-silico dose escalation to the pr...

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Bibliographic Details
Main Authors: Chemu, H. (Author), Devlin, L. (Author), Duffton, A. (Author), Grocutt, L. (Author), Hunter, B. (Author), Macleod, N. (Author), McDonald, A. (Author), McLoone, P. (Author), O'Cathail, S.M (Author)
Format: Article
Language:English
Published: Elsevier Ireland Ltd 2022
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