Local translation provides the asymmetric distribution of CaMKII required for associative memory formation

Local translation provides the asymmetric distribution of CaMKII required for associative memory formation

How compartment-specific local proteomes are generated and maintained is inadequately understood, particularly in neurons, which display extreme asymmetries. Here we show that local enrichment of Ca2+/calmodulin-dependent protein kinase II (CaMKII) in axons of Drosophila mushroom body neurons is nec...

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Bibliographic Details
Main Authors: Adel, M. (Author), Bakthavachalu, B. (Author), Chen, N. (Author), Griffith, L.C (Author), Kuklin, E.A (Author), Mardovin, J.D (Author), Ramaswami, M. (Author), Reed, M.L (Author), VijayRaghavan, K. (Author), Zhang, Y. (Author)
Format: Article
Language:English
Published: Cell Press 2022
Subjects:
axonal translation
calcium/calmodulin-dependent protein kinase II
Drosophila
mushroom body
RNA-binding protein
synaptic plasticity
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