Immunogenic dynamics and SARS-CoV-2 variant neutralisation of the heterologous ChAdOx1-S/BNT162b2 vaccination: Secondary analysis of the randomised CombiVacS study

Immunogenic dynamics and SARS-CoV-2 variant neutralisation of the heterologous ChAdOx1-S/BNT162b2 vaccination: Secondary analysis of the randomised CombiVacS study

Background: The CombiVacS study was designed to assess immunogenicity and reactogenicity of the heterologous ChAdOx1-S/BNT162b2 combination, and 14-day results showed a strong immune response. The present secondary analysis addresses the evolution of humoral and cellular response up to day 180. Meth...

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Main Authors: Agustí, A. (Author), Alcamí, J. (Author), Arana-Arri, E. (Author), Arribas, J.-R (Author), Ascaso, A. (Author), Belda-Iniesta, C. (Author), Bermejo, M. (Author), Bertrán, M.J (Author), Borobia, A.M (Author), Campins, M. (Author), Carcas, A. (Author), Castaño, L. (Author), Castillo de la Osa, M. (Author), CombiVacS study Group (Author), Conde, P. (Author), Erick de la Torre-Tarazona, H. (Author), Frías, J. (Author), Fuentes, I. (Author), García-Morales, M.T (Author), García-Pérez, J. (Author), Gómez de la Cámara, A. (Author), González-Pérez, M. (Author), Hernández-Gutierrez, L. (Author), Imaz-Ayo, N. (Author), Lora, D. (Author), Mellado-Pau, E. (Author), Ochando, J. (Author), Pérez-Ingidua, C. (Author), Pérez-Olmeda, M. (Author), Portolés, A. (Author), Tortajada, M. (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2022
Subjects:
Antibodies
Heterologous vaccination
Neutralisation
SARS-CoV-2
Variants
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