Immune response and reactogenicity after immunization with two-doses of an experimental COVID-19 vaccine (CVnCOV) followed by a third-fourth shot with a standard mRNA vaccine (BNT162b2): RescueVacs multicenter cohort study

Immune response and reactogenicity after immunization with two-doses of an experimental COVID-19 vaccine (CVnCOV) followed by a third-fourth shot with a standard mRNA vaccine (BNT162b2): RescueVacs multicenter cohort study

Background: There is no evidence to date on immunogenic response among individuals who participated in clinical trials of COVID-19 experimental vaccines redirected to standard national vaccination regimens. Methods: This multicentre, prospective controlled cohort study included subjects who received...

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Main Authors: Alcamí, J. (Author), Arana-Arri, E. (Author), Arrizabalaga, J. (Author), Ascaso-del-Rio, A. (Author), Astasio González, O. (Author), Bermejo, M. (Author), Castillo de la Osa, M. (Author), de la Torre-Tarazona, H.E (Author), Díez-Fuertes, F. (Author), García-Pérez, J. (Author), Hernández Gutiérrez, L. (Author), Imaz-Ayo, N. (Author), Mariano Lázaro, A. (Author), Meijide, S. (Author), Pérez-Ingidua, C. (Author), Pérez-Olmeda, M. (Author), Portolés, A. (Author), RescueVac study Group (Author), Riaño Fernández, I. (Author), Vargas-Castrillón, E. (Author), Vergara, I. (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2022
Subjects:
Antibodies
BNT162b2
Boost doses of vaccines
COVID-19 vaccines
CVnCoV
Experimental vaccines
Fourth dose
Heterologous vaccination
Immune response
mRNA vaccines
neutralizing antibodies
Omicron
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