In vivo biodistribution of edelfosine-loaded lipid nanoparticles radiolabeled with Technetium-99 m: Comparison of administration routes in mice

Edelfosine (ET) is a potent antitumor agent but causes severe side effects that have limited its use in clinical practice. For this reason, nanoencapsulation in lipid nanoparticles (LNs) is advantageous as it protects from ET side-effects. Interestingly, previous studies showed the efficacy of LNs c...

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Bibliographic Details
Main Authors: Blanco-Prieto, M.J (Author), Bouziotis, P. (Author), El Moukhtari, S.H (Author), Lasa-Saracíbar, B. (Author), Loudos, G. (Author), Tsotakos, T. (Author), Xanthopoulos, S. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2022
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