Alzheimer's disease amyloid-β pathology in the lens of the eye

Alzheimer's disease amyloid-β pathology in the lens of the eye

Neuropathological hallmarks of Alzheimer's disease (AD) include pathogenic accumulation of amyloid-β (Aβ) peptides and age-dependent formation of amyloid plaques in the brain. AD-associated Aβ neuropathology begins decades before onset of cognitive symptoms and slowly progresses over the course...

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Bibliographic Details
Main Authors: Alvarez, V.E (Author), Burton, M.A (Author), Chadwick, O. (Author), Clark, J.I (Author), Ericsson, M. (Author), Goldstein, L.E (Author), McKee, A.C (Author), Minaeva, O. (Author), Moir, R.D (Author), Moncaster, J.A (Author), Tanzi, R.E (Author)
Format: Article
Language:English
Published: Academic Press 2022
Subjects:
Alzheimer's disease
Amyloid precursor protein
Amyloid-β
Aβ
Biomarker
Cataract
Down syndrome
Lens
Protein aggregation
Quasi-elastic light scattering
Transgenic mouse model
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