Epileptiform GluN2B–driven excitation in hippocampus as a therapeutic target against temporal lobe epilepsy

GluN2B is an NMDAR subunit that displays restricted expression in the mature hippocampus - a structure playing a major role in temporal lobe epilepsy. However, the contribution of GluN2B to the pathophysiology of the condition has not been fully explored. Here we combined status epilepticus models o...

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Bibliographic Details
Main Authors: Gorlewicz, A. (Author), Kaczmarek, L. (Author), Knapska, E. (Author), Orlova, K. (Author), Pijet, B. (Author)
Format: Article
Language:English
Published: Academic Press Inc. 2022
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