Hydrogen sulfide alleviates particulate matter-induced emphysema and airway inflammation by suppressing ferroptosis

Hydrogen sulfide alleviates particulate matter-induced emphysema and airway inflammation by suppressing ferroptosis

Background: Redox imbalance is an vital mechanism for COPD. At present, insufficient researches have been conducted on the protective effect of hydrogen sulfide (H2S) on PM-induced COPD. However, whether H2S exerts the anti-injury role by blocking ferroptosis and restoring redox equilibrium remain t...

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Bibliographic Details
Main Authors: Chen, Y. (Author), Fan, J. (Author), Jiang, S. (Author), Liao, S. (Author), Liu, T. (Author), Ma, S. (Author), Pan, Z. (Author), Wang, Y. (Author), Xue, L. (Author), Yang, J. (Author), Yu, S. (Author), Zhang, J. (Author)
Format: Article
Language:English
Published: Elsevier Inc. 2022
Subjects:
Chronic obstructive pulmonary disease
Ferritinophagy
Ferroptosis
Hydrogen sulfide
Lipid peroxidation
Nrf2
PM2.5
PPAR-γ
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