Sc(OTf)3-catalyzed synthesis of polysubstituted furans from acylacetonitriles and renewable acetol

A [3 ​+ ​2] cyclization reaction of acylacetonitriles and hydroxyacetone was developed by using Sc(OTf)3 as a catalyst to synthesize some furan derivatives. Bifunctional C2-based acetals, such as α-bromoacetaldehyde acetal, 1,4-dithiane-2,5-diol and glycolaldehyde diethyl acetal, also reacted readil...

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Bibliographic Details
Main Authors: Bei, M. (Author), Fang, W. (Author), Gu, Y. (Author), Huang, W. (Author), Ke, S. (Author), Li, M. (Author), Liu, F. (Author), Sidorenko, A. (Author), Wang, K. (Author), Zhang, Z. (Author)
Format: Article
Language:English
Published: KeAi Communications Co. 2022
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