Defining the mechanism of PDI interaction with disulfide-free amyloidogenic proteins: Implications for exogenous protein expression and neurodegenerative disease

Protein disulfide isomerase (PDI) is an important molecular chaperone capable of facilitating protein folding in addition to catalyzing the formation of a disulfide bond. To better understand the distinct substrate-screening principles of Pichia pastoris PDI (Protein disulfide isomerase) and the pro...

Full description

Bibliographic Details
Main Authors:	Chang, A.K (Author), He, J. (Author), Jones, G.W (Author), Liu, D. (Author), Milton, N.G.N (Author), Niu, T. (Author), Wang, R. (Author), Yan, P. (Author), Zhang, S. (Author), Zhang, X. (Author), Zhou, X. (Author), Zou, Z. (Author)
Format:	Article
Language:	English
Published:	Elsevier B.V. 2021
Subjects:	alpha synuclein alpha-Synuclein amyloid beta protein amyloid beta protein[1-42] Amyloid beta-Peptides amyloid protein Amyloidogenic protein Amyloidogenic Proteins Article binding affinity budding yeast cell protein chaperone chemistry Chromatography, Liquid degenerative disease disulfide Disulfides endoplasmic reticulum Endoplasmic Reticulum enzymology fungal strain gene expression Gene Expression genetics Komagataella pastoris liquid chromatography mass spectrometry Mass Spectrometry metabolism Molecular chaperone Molecular Chaperones molecular docking Molecular Docking Simulation molecular mechanics nonhuman physiology Pichia procedures protein analysis protein binding protein disulfide isomerase Protein disulfide isomerase Protein Disulfide-Isomerases protein expression protein folding Protein Folding protein processing Protein Processing, Post-Translational protein protein interaction protein SAA1 proteomics Proteomics Saccharomycetales serum amyloid A Serum Amyloid A Protein unclassified drug
Online Access:	View Fulltext in Publisher

Internet

View Fulltext in Publisher

Defining the mechanism of PDI interaction with disulfide-free amyloidogenic proteins: Implications for exogenous protein expression and neurodegenerative disease

Internet

Similar Items