Notable sequence homology of the ORF10 protein introspects the architecture of SARS-CoV-2

Notable sequence homology of the ORF10 protein introspects the architecture of SARS-CoV-2

The current Coronavirus Disease 19 (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) shows similar pathology to MERS and SARS-CoV, with a current estimated fatality rate of 1.4%. Open reading frame 10 (ORF10) is a unique SARS-CoV-2 accessory protein, which c...

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Bibliographic Details
Main Authors: Abd El-Aziz, T.M (Author), Adadi, P. (Author), Aljabali, A.A.A (Author), Attrish, D. (Author), Azad, G.K (Author), Baetas-da-Cruz, W. (Author), Barh, D. (Author), Brufsky, A.M (Author), Choudhury, P.P (Author), Ghosh, S. (Author), Hassan, S.S (Author), Kandimalla, R. (Author), Lal, A. (Author), Lundstrom, K. (Author), Palù, G. (Author), Pizzol, D. (Author), Rezaei, N. (Author), Serrano-Aroca, Á (Author), Seyran, M. (Author), Sherchan, S.P (Author), Soares, A. (Author), Takayama, K. (Author), Tambuwala, M.M (Author), Uhal, B.D (Author), Uversky, V.N (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2021
Subjects:
amino acid sequence
antigenicity
Article
binding affinity
cell cloning
comparative study
controlled study
coronavirus disease 2019
coronavirus spike glycoprotein
COVID-19
cytotoxic T lymphocyte
epitope
Epitopes, T-Lymphocyte
gene mutation
genetic database
genetic variability
genetics
Genome, Viral
human
Humans
in vivo study
Intrinsic disorder
metabolism
missense mutation
mortality rate
mutation
Mutation
Mutations
open reading frame
open reading frame 10 protein
Open Reading Frames
ORF10
Pangolin coronavirus
Pangolin-CoV-2020
pathogenesis
physical chemistry
protein expression
SARS-CoV-2
sequence analysis
sequence homology
Sequence Homology
Severe acute respiratory syndrome coronavirus 2
Spike Glycoprotein, Coronavirus
structure analysis
tyrosine
unclassified drug
Viral Nonstructural Proteins
viral protein
Viral Proteins
virology
virus genome
virus morphology
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