Molecular characterization, expression and functional analysis of yak IFITM3 gene

Molecular characterization, expression and functional analysis of yak IFITM3 gene

IFITM3 is interferon-induced transmembrane 3, which plays an extremely key role in anti-proliferation, anti-virus and anti-tumor diseases. In this study, the yak (Bos grunniens) IFITM3 (BgIFITM3) gene contained a 5′-untranslated region (UTR) (25 bp), a coding region (441 bp), and a 3′-UTR (115 bp)....

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Bibliographic Details
Main Authors: Fu, F. (Author), Li, J. (Author), Wang, H. (Author), Wang, L. (Author), Zhang, L. (Author), Zheng, Y. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2021
Subjects:
3' untranslated region
3' Untranslated Regions
5' untranslated region
5' Untranslated Regions
animal
animal cell
animal experiment
animal tissue
Animals
Article
bioinformatics
bovine
cardiac muscle
Cattle
cell proliferation
Cell Proliferation
cell survival
Cell Survival
chemistry
cholecystokinin octapeptide
Cloning, Molecular
colony formation
controlled study
drug effect
epidermal growth factor receptor 2
ferroptosis
Ferroptosis
gene expression
genetic transcription
genetics
glutathione peroxidase
heart
Hepatocyte
HepG2
Hep-G2 cell line
human
human cell
Humans
IFITM3
immunohistochemistry
insulin receptor substrate 1
interferon
kidney
Kidney
liver
Liver
liver cell
lung
Lung
MCF-7 cell line
MCF-7 Cells
membrane protein
Membrane Proteins
metabolism
mitogen activated protein kinase 3
molecular cloning
molecular weight
Molecular Weight
Myocardium
nonhuman
PI3K/Akt
Pi3K/Akt signaling
procedures
protein expression
Raf protein
real time polymerase chain reaction
scar formation
spleen
Spleen
tissue distribution
Tissue Distribution
transmission electron microscopy
tumor suppressor gene
untranslated region
voltage dependent anion channel 2
voltage dependent anion channel 3
Western blotting
yak
Yak
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