Determinants of antidepressant response: Implications for practice and future clinical trials

Determinants of antidepressant response: Implications for practice and future clinical trials

Background: Response to antidepressants in major depressive disorder is variable and determinants are not well understood or used to design clinical trials. We aimed to understand these determinants. Methods: Supported by Innovative Medicines Initiative, as part of a large public-private collaborati...

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Bibliographic Details
Main Authors: Kapur, S. (Author), Mandel, F.S (Author), Marangell, L. (Author), Menard, F. (Author), Rabinowitz, J. (Author), Werbeloff, N. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2018
Subjects:
adult
Adult
antidepressant agent
Antidepressive Agents
Article
clinical outcome
Depressive Disorder, Major
drug approval
Drug Approval
drug resistance
Drug Resistance
female
Female
Hamilton Depression Rating Scale
human
Humans
major depression
male
Male
middle aged
Middle Aged
Montgomery Asberg Depression Rating Scale
placebo effect
Placebo Effect
priority journal
proof of concept
Psychiatric Status Rating Scales
psychological rating scale
randomized controlled trial (topic)
Randomized Controlled Trials as Topic
sample size
Sample Size
statistics and numerical data
treatment outcome
Treatment Outcome
treatment response
United States
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