RGS14 regulates PTH- and FGF23-sensitive NPT2A-mediated renal phosphate uptake via binding to the NHERF1 scaffolding protein

RGS14 regulates PTH- and FGF23-sensitive NPT2A-mediated renal phosphate uptake via binding to the NHERF1 scaffolding protein

Phosphate homeostasis, mediated by dietary intake, renal absorption, and bone deposition, is incompletely understood because of the uncharacterized roles of numerous implicated protein factors. Here, we identified a novel role for one such element, regulator of G protein signaling 14 (RGS14), sugges...

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Bibliographic Details
Main Authors: Emlet, D.R (Author), Friedman, P.A (Author), Gefter, J.V (Author), Harbin, N.H (Author), Hepler, J.R (Author), Magyar, C.E (Author), Mamonova, T. (Author), Montanez-Miranda, C. (Author), Ramineni, S. (Author), Sneddon, W.B (Author), Squires, K.E (Author)
Format: Article
Language:English
Published: American Society for Biochemistry and Molecular Biology Inc. 2022
Subjects:
Binding energy
Bone
Cell culture
Dietary intakes
Energy transfer
Fibroblast growth factor-23
Fibroblasts
G protein
Homoeostasis
Hormones growth
Ligands
Parathyroid hormones
Phosphate uptake
Protein signaling
Proteins
Regulatory factors
Scaffolding proteins
Scaffolds (biology)
Sodium compounds
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