Fluorescence lifetime imaging microscopy reveals sodium pump dimers in live cells

Fluorescence lifetime imaging microscopy reveals sodium pump dimers in live cells

The sodium-potassium ATPase (Na/K-ATPase, NKA) establishes ion gradients that facilitate many physiological functions including action potentials and secondary transport processes. NKA comprises a catalytic subunit (alpha) that interacts closely with an essential subunit (beta) and regulatory transm...

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Bibliographic Details
Main Authors: Bossuyt, J.B (Author), Cleary, S.R (Author), Espinoza-Fonseca, L.M (Author), Fang, X. (Author), Habibi, N.R (Author), Kekenes-Huskey, P.M (Author), Robia, S.L (Author), Seflova, J. (Author), Yap, J.Q (Author)
Format: Article
Language:English
Published: American Society for Biochemistry and Molecular Biology Inc. 2022
Subjects:
Alpha-beta
Association reactions
ATPases
Beta subunit
Catalytic subunits
Dimers
Electrophysiology
Fluorescence imaging
Fluorescence lifetime imaging microscopy
Ion gradients
Live cell
Molecular dynamics
Physiological functions
Proteins
Regulatory complexes
Sodium
Sodium/potassium-ATPase
Stoichiometry
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