PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c

PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c

The double-stranded RNA-dependent protein kinase activating protein (PACT), an RNA-binding protein that is part of the RNA-induced silencing complex, plays a key role in miR-mediated translational repression. Previous studies showed that PACT regulates the expression of various miRs, selects the miR...

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Bibliographic Details
Main Authors: Dogan, A.E (Author), Erbay, E. (Author), Gottlieb, R.A (Author), Hamid, S.M (Author), Riera, C.E (Author), Sen, G. (Author), Yildirim, A.D (Author), Yildirim, Z. (Author)
Format: Article
Language:English
Published: American Society for Biochemistry and Molecular Biology Inc. 2022
Subjects:
Adipose tissue
Biological organs
Biosynthesis
Brakes
brown adipose tissue
Brown adipose tissue
Chemical activation
Double-stranded RNA
Mammals
micro-RNA
Micro-RNA
mitochondria
Mitochondria
mitochondrial biogenesis
Mitochondrial biogenesis
Mitochondrias
Post-transcriptional
Proteins
RNA
RNA-dependent protein kinase
RNAi
RNA-induced silencing complexes
Tissue
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