In vitro eradication of abasic site-mediated DNA–peptide/protein cross-links by Escherichia coli long-patch base excision repair
Apurinic/apyrimidinic (AP or abasic) sites are among the most abundant DNA lesions. Numerous proteins within different organisms ranging from bacteria to human have been demonstrated to react with AP sites to form covalent Schiff base DNA–protein cross-links (DPCs). These DPCs are unstable due to th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Biochemistry and Molecular Biology Inc.
2022
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |