Fucoidan from Fucus versiculosus can inhibit human norovirus replication by enhancing the host innate immune response

Fucoidan from Fucus versiculosus can inhibit human norovirus replication by enhancing the host innate immune response

Fucoidan extracted from Fucus versiculosus was able to inhibit the replication of human noroviruses (hNoV) GII.4[P16] in zebrafish (Danio rerio) larvae. In the hNoV infected zebrafish larvae, a transcriptomic analysis showed significant upregulation (p < 0.01) of the interferons (IFNs) signaling...

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Bibliographic Details
Main Authors: Eshaghi Gorji, M. (Author), Gong, Z. (Author), Li, D. (Author), Li, Y. (Author), Park, A.Y (Author), Tan, M.T.H (Author), Toh, J.Y.L (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2022
Subjects:
Antiviral
Fucoidan
Global transcriptional analysis
hNoV
Innate immune response
Interferon
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