Dysregulation of Hepatitis B Virus Nucleocapsid Assembly in vitro by RNA-binding Small Ligands

Dysregulation of Hepatitis B Virus Nucleocapsid Assembly in vitro by RNA-binding Small Ligands

RNA sequences/motifs dispersed across the genome of Hepatitis B Virus regulate formation of nucleocapsid-like particles (NCPs) by core protein (Cp) in vitro, in an epsilon/polymerase-independent fashion. These multiple RNA Packaging Signals (PSs) can each form stem-loops encompassing a Cp-recognitio...

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Bibliographic Details
Main Authors: Abulwerdi, F. (Author), Fatehi, F. (Author), Le Grice, S. (Author), Manfield, I.W (Author), Patel, N. (Author), Schneekloth, J.S., Jr (Author), Stockley, P.G (Author), Twarock, R. (Author)
Format: Article
Language:English
Published: Academic Press 2022
Subjects:
directly-acting anti-virals
hepatitis B virus
packaging-signal mediated assembly
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