A data-driven approach for the detection of internal standard outliers in targeted LC-MS/MS assays
Heavy-labelled internal standard (IS) compounds are commonly used in liquid chromatography-tandem mass spectrometry (LC-MS/MS) assays to control for stochastic and systematic variation. Identifying samples that suffer from unwanted variation is critically important in order to avoid factitiously ina...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier B.V.
2021
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |