ZnO nanoparticles attenuate polymer-wear-particle induced inflammatory osteolysis by regulating the MEK-ERK-COX-2 axis

Background/Objectives: Advanced thermoplastic materials, such as polyether-ether-ketone (PEEK) and highly cross-linked polyethylene (HXLPE), have been increasingly used as orthopaedic implant materials. Similar to other implants, PEEK-on-HXLPE prostheses produce debris from polymer wear that may act...

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Bibliographic Details
Main Authors: Long, T. (Author), Lyu, Z. (Author), Meng, X. (Author), Wang, Y. (Author), Zhang, W. (Author)
Format: Article
Language:English
Published: Elsevier (Singapore) Pte Ltd 2022
Subjects:
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