Taxifolin stability: In silico prediction and in vitro degradation with HPLC-UV/UPLC–ESI-MS monitoring

Taxifolin stability: In silico prediction and in vitro degradation with HPLC-UV/UPLC–ESI-MS monitoring

Taxifolin has a plethora of therapeutic activities and is currently isolated from the stem bark of the tree Larix gmelinni (Dahurian larch). It is a flavonoid of high commercial interest for its use in supplements or in antioxidant-rich functional foods. However, its poor stability and low bioavaila...

Full description

Bibliographic Details
Main Authors: Bellé Bresolin, T.M (Author), Bonomini, T.J (Author), Cechinel-Filho, V. (Author), dos Santos Machado, C.L (Author), Garcia Couto, A. (Author), Reisdorfer Paula, F. (Author), Ricci, M. (Author), Sandjo, L.P (Author), Stenger Moura, F.C (Author)
Format: Article
Language:English
Published: Xi'an Jiaotong University 2021
Subjects:
acetonitrile
alkaline hydrolysis
Article
autooxidation
carbon nuclear magnetic resonance
chemical structure
chromatography
comparative study
computer model
contact time
controlled study
density functional theory
Dihydroquercetin
dissociation
drug bioavailability
drug degradation
electrophilicity
electrospray mass spectrometry
Forced degradation
high performance liquid chromatography
humidity
hydrogen
hydrolysis
In silico stability prediction
in vitro study
infrared spectroscopy
ionization
limit of detection
limit of quantitation
liquid chromatography-mass spectrometry
methanol
nonhuman
nucleophilicity
oxidation
particle size
pH
phosphoric acid
prediction
proton nuclear magnetic resonance
quercetin
retention time
stainless steel
surface property
taxifolin
ultra performance liquid chromatography
ultraviolet radiation
water
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items