Accurate and sensitive determination of hydroxychloroquine sulfate used on COVID-19 patients in human urine, serum and saliva samples by GC-MS

Accurate and sensitive determination of hydroxychloroquine sulfate used on COVID-19 patients in human urine, serum and saliva samples by GC-MS

A rapid, accurate, and sensitive analytical method, ultrasonication-assisted spraying based fine droplet formation–liquid phase microextraction–gas chromatography–mass spectrometry (UA-SFDF-LPME-GC-MS), was proposed for the determination of trace amounts of hydroxychloroquine sulfate in human serum,...

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Bibliographic Details
Main Authors: Bakırdere, S. (Author), Bodur, S. (Author), Erarpat, S. (Author), Günkara, Ö.T (Author)
Format: Article
Language:English
Published: Xi'an Jiaotong University 2021
Subjects:
accuracy
analytic method
aqueous solution
Article
Biological samples
blood sampling
chloroform
coronavirus disease 2019
dichloroethane
dichloromethane
Dispersive solid phase extraction
GC-MS
human
hydroxychloroquine sulfate
Hydroxychloroquine sulfate
limit of detection
limit of quantitation
liquid phase microextraction
Liquid phase microextraction
mass fragmentography
post hoc analysis
saliva analysis
serum
sodium hydroxide
solid phase extraction
solubility
solvent
solvent extraction
ultrasound assisted extraction
urine sampling
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