Identification of lysine acetylome of oral squamous cell carcinoma by label-free quantitative proteomics

Identification of lysine acetylome of oral squamous cell carcinoma by label-free quantitative proteomics

Lysine acetylation (Kac) on histone promotes relaxation of the chromatin conformation and favors gene transcription to regulate oncogenesis, whereas the total acetylation profiling of oral squamous cell carcinoma (OSCC) is unknown. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) was utilis...

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Bibliographic Details
Main Authors: Cai, W. (Author), Dai, Y. (Author), Dong, J. (Author), He, J. (Author), Lai, L. (Author), Li, D. (Author), Li, Y. (Author), Shen, L. (Author), Tang, D. (Author), Tang, J. (Author), Xie, H. (Author), Yin, L. (Author), Yun, M. (Author), Zeng, Z. (Author), Zhang, W. (Author), Zhang, Z. (Author), Zuo, W. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2022
Subjects:
Head and neck cancer
Lysine acetylation
mRNA splicing
Oral cancer
Oral squamous cell carcinoma
Posttranslational modification
Ribosome pathway
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