Synthesis, anticancer, molecular docking and QSAR studies of benzoylhydrazone

Synthesis, anticancer, molecular docking and QSAR studies of benzoylhydrazone

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To find out effective anticancer compounds we synthesized (1–30) derivatives of 4-isopropylbenzoylhydrazone and evaluated for anticancer potential. The compounds 3, 9, 12, 23, 26 and 28 showed better activities ranging (0.39–1.1 µg/ml) than the standard (1.53 ± 0.01 µg/ml). In line with this, compou...

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Bibliographic Details
Main Authors: Ashraf, K. (Author), Fatmi, M.Q (Author), Halim, S.A (Author), Herizal, M. (Author), Lim, S.M (Author), Rahim, F. (Author), Ramasamy, K. (Author), Selvaraj, M. (Author), Shehzad, A. (Author), Sultan, S. (Author), Taha, M. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2019
Subjects:
4-Isopropylbenzohydrazones
Anticancer
Molecular docking
QSAR studies
Synthesis
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