In silico investigations of intratumoral heterogeneous interstitial fluid pressure

Recent preclinical studies have shown that interstitial fluid pressure (IFP) within tumors can be heterogeneous Andersen et al. (2019). In that study tumors of two xenograft models, respectively, HL-16 cervical carcinoma and Panc-1 pancreatic carcinoma, were investigated. Significant heterogeneity i...

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Bibliographic Details
Main Authors:	Evje, S. (Author), Gaustad, J.-V (Author), Rofstad, E.K (Author), Waldeland, J.O (Author)
Format:	Article
Language:	English
Published:	Academic Press 2021
Subjects:	Article blood vessel density cell cell compartmentalization cell density cell function cell interaction cell isolation cell volume Cervical carcinoma chemotaxis computer simulation Computer Simulation controlled study experimental study extracellular fluid Extracellular Fluid extracellular matrix Extracellular Matrix fibroblast fluid pressure human human cell human tissue Humans hydraulic conductivity in vitro study interstitial fluid Interstitial fluid Interstitial fluid pressure mathematical model Mathematical model Metastatic propensity microvasculature Migration mechanism neoplasm Neoplasms numerical model pancreas carcinoma Pancreatic carcinoma pressure Pressure propensity score tissue pressure tumor tumor cell Tumor progression uterine cervix carcinoma
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In silico investigations of intratumoral heterogeneous interstitial fluid pressure

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