Phenotypic variation modulates the growth dynamics and response to radiotherapy of solid tumours under normoxia and hypoxia
In cancer, treatment failure and disease recurrence have been associated with small subpopulations of cancer cells with a stem-like phenotype. In this paper, we develop and investigate a phenotype-structured model of solid tumour growth in which cells are structured by a stemness level, which varies...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Academic Press
2021
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |