Rolling-circle and strand-displacement mechanisms for non-enzymatic RNA replication at the time of the origin of life

It is likely that RNA replication began non-enzymatically, and that polymerases were later selected to speed up the process. We consider replication mechanisms in modern viruses and ask which of these is possible non-enzymatically, using mathematical models and experimental data found in the literat...

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Bibliographic Details
Main Authors: Higgs, P.G (Author), Tupper, A.S (Author)
Format: Article
Language:English
Published: Academic Press 2021
Subjects:
RNA
Online Access:View Fulltext in Publisher