Comparative Analysis of T-Cell Spatial Proteomics and the Influence of HIV Expression

Comparative Analysis of T-Cell Spatial Proteomics and the Influence of HIV Expression

As systems biology approaches to virology have become more tractable, highly studied viruses such as HIV can now be analyzed in new unbiased ways, including spatial proteomics. We employed here a differential centrifugation protocol to fractionate Jurkat T cells for proteomic analysis by mass spectr...

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Bibliographic Details
Main Authors: Gonzalez, D.J (Author), Guatelli, J. (Author), Krogan, N.J (Author), Lewinski, M.K (Author), Oom, A.L (Author), Richards, A. (Author), Shams-Ud-Doha, K. (Author), Stoneham, C.A (Author), Wozniak, J.M (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
Bayes theorem
Bayes Theorem
computational biology
differential centrifugation
genetics
HIV
HIV Infections
HIV-1
human
Human immunodeficiency virus 1
Human immunodeficiency virus infection
Humans
inducible HIV
Jurkat T cells
mass spectrometry
metabolism
proteome
Proteome
proteomics
Proteomics
spatial proteomics
subcellular fractionation
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