Maresin-2 alleviates allergic airway inflammation in mice by inhibiting the activation of NLRP3 inflammasome, Th2 type immune response and oxidative stress

Asthma is a chronic inflammatory disease of the respiratory system. Maresin-2 (MaR2) is biosynthesized from docosahexaenoic acid (DHA) by macrophages, display strong anti-inflammatory and pro-resolving activity. To investigate the therapeutic effect and mechanism of MaR2 on asthmatic mice induced by...

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Bibliographic Details
Main Authors: Chen, J.-J (Author), Chen, X.-J (Author), Liu, Q. (Author), Nie, X.-J (Author), Ou, G.-C (Author), Shi, Z.-A (Author), Yu, C.-X (Author), Zeng, D. (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2022
Subjects:
ASC
MPO
Online Access:View Fulltext in Publisher