Central deficiency of IL-6Ra in mice impairs glucose-stimulated insulin secretion

Central deficiency of IL-6Ra in mice impairs glucose-stimulated insulin secretion

Objective: IL-6 is an important contributor to glucose and energy homeostasis through changes in whole-body glucose disposal, insulin sensitivity, food intake and energy expenditure. However, the relative contributions of peripheral versus central IL-6 signaling to these metabolic actions are presen...

Full description

Bibliographic Details
Main Authors: Ashford, M.L (Author), Gallagher, J.G (Author), McCrimmon, R.J (Author), McNeilly, A.D (Author), Tarlton, J. (Author), Yianakas, A. (Author)
Format: Article
Language:English
Published: Elsevier GmbH 2022
Subjects:
Autonomic output
Energy expenditure
Food intake
Insulin secretion
Interleukin-6
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items