Effects of Eph/ephrin signalling and human Alzheimer's disease-associated EphA1 on Drosophila behaviour and neurophysiology

Effects of Eph/ephrin signalling and human Alzheimer's disease-associated EphA1 on Drosophila behaviour and neurophysiology

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease placing a great burden on people living with it, carers and society. Yet, the underlying patho-mechanisms remain unknown and treatments limited. To better understand the molecular changes associated with AD, genome-wide as...

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Bibliographic Details
Main Authors: Buhl, E. (Author), Hodge, J.J.L (Author), Kim, Y.A (Author), Lefort, R. (Author), Parsons, T. (Author), Santa-Maria, I. (Author), Zhu, B. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
Alzheimer disease
Alzheimer Disease
Alzheimer's disease
animal
Animals
Ca(2+)imaging
Circadian rhythms
degenerative disease
Drosophila
Drosophila melanogaster
Electrophysiology
Eph/ephrin signalling
ephrin
ephrin receptor
Ephrins
genetics
genome-wide association study
Genome-Wide Association Study
human
Humans
Locomotor activity
Longevity
Memory
Neurodegenerative Diseases
neurophysiology
Neurophysiology
Receptors, Eph Family
Sleep
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