Prognostic value of integrin αV expression and localization pattern in invasive breast carcinomas

Prognostic value of integrin αV expression and localization pattern in invasive breast carcinomas

Invasion of surrounding stroma is an early event in breast cancer metastatic progression, and involves loss of cell polarity, loss of myoepithelial layer, epithelial-mesenchymal transition (EMT) and remodeling of the extracellular matrix (ECM). Integrins are transmembrane receptors responsible for c...

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Bibliographic Details
Main Authors: Botelho, M.C.S (Author), Bruni-Cardoso, A. (Author), Cardoso, E.C (Author), Cerqueira, O.L.D (Author), Fiore, A.P.Z.P (Author), López, R.V.M (Author), Morais, M.C.C (Author), Osório, C.A.B.D.T (Author), Reis, E.M (Author), Tomasin, R. (Author), Vilella-Arias, S.A (Author)
Format: Article
Language:English
Published: Elsevier Inc. 2022
Subjects:
3D cell culture
Breast cancer
Integrin αV
Metastasis
Tissue microarray
Tumor stroma
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