Impact of spill-in counts from off-target regions on [18F]Flortaucipir PET quantification

Impact of spill-in counts from off-target regions on [18F]Flortaucipir PET quantification

Background: [18F]Flortaucipir (FTP) PET quantification is usually hindered by spill-in counts from off-target binding (OFF) regions. The present work aims to provide an in-depth analysis of the impact of OFF in FTP PET quantification, as well as to identify optimal partial volume correction (PVC) st...

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Bibliographic Details
Main Authors: Aguiar, P. (Author), Costoya-Sánchez, A. (Author), for the Alzheimer's Disease Neuroimaging Initiative (Author), López-González, F.J (Author), Moscoso, A. (Author), Paredes-Pacheco, J. (Author), Silva-Rodríguez, J. (Author)
Format: Article
Language:English
Published: Academic Press Inc. 2022
Subjects:
Monte Carlo
Off-target binding
PVE
SUVR
Tau PET
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