Dopamine-related dissociation of cortical and subcortical brain activations in cognitively unimpaired Parkinson's disease patients OFF and ON medications

Dopamine-related dissociation of cortical and subcortical brain activations in cognitively unimpaired Parkinson's disease patients OFF and ON medications

Background: Despite dopaminergic depletion that is severe enough to cause the motor symptoms of Parkinson's disease (PD), many patients remain cognitively unimpaired. Little is known about brain mechanisms underlying such preserved cognitive abilities and their alteration by dopaminergic medica...

Full description

Bibliographic Details
Main Authors: Cai, W. (Author), Kim, J. (Author), Llanes, S. (Author), Menon, V. (Author), Poston, K.L (Author), Ua Cruadhlaoich, M.A.I (Author), YorkWilliams, S. (Author), Zhang, K. (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2018
Subjects:
adult
aged
amantadine
anterior insula
antiparkinson agent
Antiparkinson Agents
Article
behavior control
brain
Brain
brain mapping
Brain Mapping
carbidopa plus levodopa
Choice Behavior
Choice Reaction Time
clinical article
cognition
Cognition
cohort analysis
Cohort Studies
controlled study
decision making
diagnostic imaging
dopamine
Dopamine
drug effect
electroencephalogram
entacapone
female
Female
fMRI
frontal cortex
functional dissociation
functional magnetic resonance imaging
human
Humans
Magnetic Resonance Imaging
male
Male
measurement accuracy
mental function
metabolism
middle aged
Middle Aged
motor activity
Motor Activity
nuclear magnetic resonance imaging
Parkinson disease
Parkinson Disease
Parkinson's disease
physiology
pramipexole
psychology
putamen
rasagiline
response time
ropinirole
task performance
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items