Corticosterone differentially modulates time-dependent fear generalization following mild or moderate fear conditioning training in rats

Corticosterone differentially modulates time-dependent fear generalization following mild or moderate fear conditioning training in rats

Stressful and emotionally arousing experiences create strong memories that seem to lose specificity over time. It is uncertain, however, how the stress system contributes to the phenomenon of time-dependent fear generalization. Here, we investigated whether post-training corticosterone (CORT-HBC) in...

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Bibliographic Details
Main Authors: dos Santos Corrêa, M. (Author), Ferreira, T.L (Author), Fornari, R.V (Author), Menezes, B.S (Author), Tiba, P.A (Author), Vaz, B.D.S (Author)
Format: Article
Language:English
Published: Academic Press Inc. 2021
Subjects:
2 hydroxypropyl beta cyclodextrin
adult
amygdala
animal
animal experiment
animal model
animal tissue
Animals
Arousal
Article
basolateral amygdala
behavior
colony formation
conditioned reflex
Conditioning, Classical
controlled study
corticosterone
Corticosterone
Discrimination
dose response
Dose-Response Relationship, Drug
drug effect
Emotional memory
experimental behavioral test
fear
Fear
fear conditioning test
female
footshock
Generalization, Psychological
glucocorticoid
Glucocorticoids
hippocampus
male
Male
memory consolidation
mouse
nonhuman
novel object recognition test
posttraumatic stress disorder
rat
Rats
Rats, Wistar
Specificity
stereotaxic surgery
Stress
temperature
time factor
Time Factors
training
transcranial direct current stimulation
Wistar rat
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