Genetic differences in the behavioral organization of binge eating, conditioned food reward, and compulsive-like eating in C57BL/6J and DBA/2J strains

Genetic differences in the behavioral organization of binge eating, conditioned food reward, and compulsive-like eating in C57BL/6J and DBA/2J strains

Binge eating (BE) is a heritable symptom of eating disorders associated with anxiety, depression, malnutrition, and obesity. Genetic analysis of BE could facilitate therapeutic discovery. We used an intermittent, limited access BE paradigm involving sweetened palatable food (PF) to examine genetic d...

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Bibliographic Details
Main Authors: Babbs, R.K (Author), Bryant, C.D (Author), Kelliher, J.C (Author), Luttik, K.P (Author), Mulligan, M.K (Author), Scotellaro, J.L (Author)
Format: Article
Language:English
Published: Elsevier Inc. 2018
Subjects:
allele
animal
animal experiment
animal model
Animals
anxiety
Anxiety
Article
binge eating disorder
Binge-Eating Disorder
C57BL 6 mouse
C57BL mouse
chromosome 11
chromosome 4
chromosome 6
cohort analysis
compulsion
Compulsive Behavior
conditioning
Conditioning (Psychology)
controlled study
DBA 2 mouse
DBA mouse
drug abuse
feeding behavior
Feeding Behavior
female
Female
follow up
food
Food
genetic difference
genetic variability
genetics
genome-wide association study
Genome-Wide Association Study
GWAS
heritability
hoarding
Hoarding
hole board test
male
Male
Mice, Inbred C57BL
Mice, Inbred DBA
mouse
nonhuman
pathophysiology
phenotype
Phenotype
physiology
pleiotropy
priority journal
psychology
QTL
quantitative trait locus
reward
Reward
Sex Characteristics
sex difference
Sex differences
sexual characteristics
species difference
Species Specificity
strain difference
Sucrose
sweetness
TAS2R
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