Effect of chronic handling and social isolation on emotion and cognition in adolescent rats

Effect of chronic handling and social isolation on emotion and cognition in adolescent rats

Adolescence is a critical period of establishing social relations through social interactions that affect the emotional development associated with stress responses, anxiety, depression, and cognitive development. We investigated the behavioral and neurobiological changes induced by handling and soc...

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Bibliographic Details
Main Authors: Kim, Y.-J (Author), Lee, J.H (Author), Song, M.K (Author)
Format: Article
Language:English
Published: Elsevier Inc. 2021
Subjects:
adolescent
adolescent development
animal
animal behavior
animal experiment
animal tissue
Animals
anxiety
Anxiety
Article
behavior change
Behavior, Animal
brain analysis
cognition
Cognition
cognitive development
controlled study
depression
Depression
Depression-like behavior
dorsal raphe nucleus
emotion
Emotions
escape latency
forced swim test
glucocorticoid receptor
Handling
hippocampus
immobility time
immunohistochemistry
male
mental stress
nonhuman
open field test
passive avoidance test
priority journal
protein expression
protein expression level
rat
Rats
SIRT1
sirtuin 1
social interaction
social isolation
Social isolation
Social Isolation
Stress
Stress, Psychological
tryptophan hydroxylase
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