Comparison of two immunoassays for the measurement of serum HE4 for ovarian cancer

Comparison of two immunoassays for the measurement of serum HE4 for ovarian cancer

Introduction: The use of Human Epididymis Protein 4 (HE4) as a biomarker for ovarian cancer is gaining traction, providing the impetus for development of a high throughput automated HE4 assay that is comparable to the conventional manual enzyme immunometric-assay (EIA). The aim of this study was to...

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Bibliographic Details
Main Authors: Barr, C.E (Author), Crosbie, E.J (Author), Funston, G. (Author), Howe, J.D (Author), Mounce, L.T.A (Author), Pemberton, P.W (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2021
Subjects:
Article
automation
Biomarker
blood sampling
CA 125 antigen
calibration
chemiluminescence immunoassay
controlled study
correlation coefficient
disease marker
female
HE4
human
human cell
immunoassay
Immunoassay
intermethod comparison
manual enzyme immunometric assay
Ovarian cancer detection
ovary cancer
protein blood level
protein determination
sensitivity and specificity
WAP four-disulfide core domain protein 2
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