Immune subtraction for improved resolution in serum protein immunofixation electrophoresis and antibody isotype determination in a patient with autoantibody

Heavy chain isotypes of low level monoclonal immunoglobulins are sometimes obscured in serum immunofixation electrophoresis (SIFE) by a heavy background of polyclonal immunoglobulins. However, accurate determination of the heavy chain isotype is essential for a complete diagnosis, as isotype determi...

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Bibliographic Details
Main Authors: Bollag, R.J (Author), Omar, N. (Author), Savage, N.M (Author), Singh, G. (Author), Ullah, A. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2021
Subjects:
Online Access:View Fulltext in Publisher