Investigations into the role of inflammation in normal tissue response to irradiation

Investigations into the role of inflammation in normal tissue response to irradiation

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Purpose: Radiation-induced inflammation and production of reactive oxygen species (ROS) play a critical role in normal tissue response. In this study we have examined some aspects of these effects in lung and skin. Methods: The superoxide dismutase (SOD) catalase mimetic, EUK-207, and genistein, an...

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Bibliographic Details
Main Authors: Hill, R.P (Author), Jelveh, S. (Author), Mahmood, J. (Author), Zaidi, A. (Author)
Format: Article
Language:English
Subjects:
animal experiment
animal model
Animals
antiinflammatory agent
article
breathing rate
Cells, Cultured
controlled study
Disease Models, Animal
DNA Damage
endotoxin
Endotoxin
euk 207
female
Female
genistein
Genistein
inflammation
irradiation
knockout mouse
Linear Models
lung
Lung
lung alveolus cell
Mice
Mice, Inbred C57BL
Mice, Knockout
Micronuclei
micronucleus
Micronucleus Tests
mouse
Multivariate Analysis
nonhuman
Organometallic Compounds
plethysmograph
Pneumonitis
priority journal
Radiation
radiation pneumonia
Radiation Pneumonitis
Radiodermatitis
Rats
Rats, Sprague-Dawley
reactive oxygen metabolite
Reactive Oxygen Species
skin
Skin
skin cell
Species Specificity
superoxide dismutase
Superoxide Dismutase
tissue reaction
TNF-alpha
tumor necrosis factor alpha
tumor necrosis factor receptor 1
tumor necrosis factor receptor 2
Tumor Necrosis Factor-alpha
unclassified drug
wild type
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