Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels

Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels

Iron is an essential metal for cellular metabolism and signaling, but it has adverse effects in excess. The physiological consequences of iron deficiency are well established, yet the relationship between iron supplementation and pericellular oxygen levels in cultured cells and their downstream effe...

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Bibliographic Details
Main Authors: Altun, H.Y (Author), Bilir (Author), Caglar, T.A (Author), Eroglu, E. (Author), Keeley, T.P (Author), Malli, R. (Author), Mann, G.E (Author), Öztürk, G. (Author), Secilmis, M. (Author), Sevimli, G. (Author), Smith, M.J (Author), Yang, F. (Author), Yigit, E.N (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2022
Subjects:
Cell culture
Culture media
Ferric iron
Ferrous iron
geNOps
Hydrogen peroxide
Hyperoxia
NO bioavailability
Normoxia
Pericellular oxygen
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