Overexpression of NAG-1/GDF15 prevents hepatic steatosis through inhibiting oxidative stress-mediated dsDNA release and AIM2 inflammasome activation
Mitochondrial dysfunction and oxidative stress-mediated inflammasome activation play critical roles in the pathogenesis of the non-alcoholic fatty liver disease (NAFLD). Non-steroidal anti-inflammatory drug (NSAID)-activated gene-1 (NAG-1), or growth differentiation factor-15 (GDF15), is associated...
Main Authors: | Chen, C. (Author), Chen, J. (Author), Chen, S. (Author), Eling, T. (Author), Lin, X. (Author), Peng, H. (Author), Sang, T. (Author), Wang, X. (Author), Wang, Y. (Author), Zhao, Q. (Author) |
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Format: | Article |
Language: | English |
Published: |
Elsevier B.V.
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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