Fatty acids derived from apoptotic chondrocytes fuel macrophages FAO through MSR1 for facilitating BMSCs osteogenic differentiation

Fatty acids derived from apoptotic chondrocytes fuel macrophages FAO through MSR1 for facilitating BMSCs osteogenic differentiation

The nonunion following a fracture is associated with severe patient morbidity and economic consequences. Currently, accumulating studies are focusing on the importance of macrophages during fracture repair. However, details regarding the process by which macrophages facilitate endochondral ossificat...

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Bibliographic Details
Main Authors: Chen, J. (Author), Chen, Q. (Author), Chu, B. (Author), Fan, J. (Author), Gu, J. (Author), Hu, L.-P (Author), Huang, Z.-F (Author), Jiang, S.-H (Author), Jiang, T. (Author), Kong, F.-Q (Author), Li, Q. (Author), Liu, H. (Author), Yin, G.-Y (Author), Yu, L.-P (Author), Zhang, H.-W (Author), Zhang, L. (Author), Zhao, S.-J (Author), Zhao, X. (Author), Zheng, Z.-Y (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2022
Subjects:
Apoptotic chondrocyte
Fatty acid oxidation
Macrophage
MSR1
Osteogenic differentiation
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