How to analyse and account for interactions in mixture toxicity with toxicokinetic-toxicodynamic models

The assessment of chemical mixture toxicity is one of the major challenges in ecotoxicology. Chemicals can interact, leading to more or less effects than expected, commonly named synergism and antagonism respectively. The classic ad hoc approach for the assessment of mixture effects is based on dose...

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Bibliographic Details
Main Authors: Ashauer, R. (Author), Badder, C. (Author), Bart, S. (Author), Eagles, E.J (Author), Jager, T. (Author), Lahive, E. (Author), Robinson, A. (Author), Short, S. (Author), Spurgeon, D.J (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2022
Subjects:
Online Access:View Fulltext in Publisher