Crystal structure of the human MUS81-EME2 complex

MUS81 is an important structure-specific endonuclease responsible for the processing of stalled replication forks and recombination intermediates. In human, MUS81 functions by forming complexes with its regulatory subunits EME1 and EME2, playing distinct roles in G2/M and S phases. Although the stru...

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Bibliographic Details
Main Authors: Fang, Q. (Author), Hua, Z. (Author), Lin, Z. (Author), Luo, Z. (Author), Yuan, C. (Author), Zhang, D. (Author)
Format: Article
Language:English
Published: Cell Press 2022
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Online Access:View Fulltext in Publisher