Polynomial Mendelian randomization reveals non-linear causal effects for obesity-related traits

Causal inference is a critical step in improving our understanding of biological processes, and Mendelian randomization (MR) has emerged as one of the foremost methods to efficiently interrogate diverse hypotheses using large-scale, observational data from biobanks. Although many extensions have bee...

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Bibliographic Details
Main Authors: Kutalik, Z. (Author), Sjaarda, J. (Author), Sulc, J. (Author)
Format: Article
Language:English
Published: Cell Press 2022
Subjects:
Online Access:View Fulltext in Publisher