Bone-conditioned medium contributes to initiation and progression of osteogenesis by exhibiting synergistic TGF-β1/BMP-2 activity

Bone-conditioned medium contributes to initiation and progression of osteogenesis by exhibiting synergistic TGF-β1/BMP-2 activity

Guided bone regeneration (GBR) often utilizes a combination of autologous bone grafts, deproteinized bovine bone mineral (DBBM), and collagen membranes. DBBM and collagen membranes pre-coated with bone-conditioned medium (BCM) extracted from locally harvested autologous bone chips have shown great r...

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Bibliographic Details
Main Authors: Asparuhova, M.B (Author), Buser, D. (Author), Caballé-Serrano, J. (Author), Chappuis, V. (Author)
Format: Article
Language:English
Published: Sichuan University Press 2018
Subjects:
biological marker
Biomarkers
BMP2 protein, human
bone development
bone morphogenetic protein 2
Bone Morphogenetic Protein 2
cell adhesion
Cell Adhesion
cell differentiation
Cell Differentiation
cell motion
Cell Movement
cell proliferation
Cell Proliferation
conditioned medium
Culture Media, Conditioned
drug effect
Guided Tissue Regeneration, Periodontal
human
Humans
mesenchymal stem cell
Mesenchymal Stem Cells
metabolism
osteoblast
Osteoblasts
Osteogenesis
periodontal guided tissue regeneration
pharmacology
procedures
transforming growth factor beta1
Transforming Growth Factor beta1
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