ERK phosphorylation functions in invadopodia formation in tongue cancer cells in a novel silicate fibre-based 3D cell culture system

ERK phosphorylation functions in invadopodia formation in tongue cancer cells in a novel silicate fibre-based 3D cell culture system

To screen for additional treatment targets against tongue cancer, we evaluated the contributions of extracellular signal-related kinase (ERK), AKT and ezrin in cancer development. Immunohistochemical staining showed that ERK and ezrin expressions were significantly higher in invasive squamous cell c...

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Bibliographic Details
Main Authors: Adachi, T. (Author), Koshinuma, S. (Author), Machida, Y. (Author), Mukaisho, K.-I (Author), Murakami, S. (Author), Nakayama, T. (Author), Noi, M. (Author), Sugihara, H. (Author), Yamamoto, G. (Author), Yamori, M. (Author), Yoshida, S. (Author)
Format: Article
Language:English
Published: Sichuan University Press 2018
Subjects:
carcinoma in situ
Carcinoma in Situ
Carcinoma, Squamous Cell
cell culture technique
Cell Culture Techniques
cell motion
Cell Movement
cell proliferation
Cell Proliferation
Cytoskeletal Proteins
cytoskeleton protein
Extracellular Signal-Regulated MAP Kinases
ezrin
human
Humans
metabolism
mitogen activated protein kinase
Neoplasm Invasiveness
pathology
phosphorylation
Phosphorylation
podosome
Podosomes
procedures
protein kinase B
Proto-Oncogene Proteins c-akt
silicon dioxide
Silicon Dioxide
squamous cell carcinoma
Tongue Neoplasms
tongue tumor
tumor cell culture
Tumor Cells, Cultured
tumor invasion
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