Neuron-specific enolase promotes stem cell-like characteristics of small-cell lung cancer by downregulating NBL1 and activating the BMP2/Smad/ID1 pathway

Neuron-specific enolase promotes stem cell-like characteristics of small-cell lung cancer by downregulating NBL1 and activating the BMP2/Smad/ID1 pathway

Little is known about the biological functions of neuron-specific enolase (NSE) as a specific biomarker for small-cell lung cancer (SCLC). Herein, we elucidate the effect and mechanism of NSE on SCLC stem cell-like characteristics. Upregulated NSE expression was observed in spheroid cells. The gain-...

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Bibliographic Details
Main Authors: Fang, X. (Author), Guan, M. (Author), Li, B. (Author), Liu, G. (Author), Liu, X. (Author), Liu, Z. (Author), Lu, L. (Author), Mao, H. (Author), Wang, L. (Author), Wang, P. (Author), Weng, C. (Author), Wu, Y. (Author), Xu, Z. (Author), Zha, Z. (Author), Zhang, P. (Author)
Format: Article
Language:English
Published: Springer Nature 2022
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